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Slow-tight-binding inhibition of enoyl-acyl carrier protein reductase from Plasmodium falciparum by triclosan

Triclosan is a potent inhibitor of FabI (enoyl-ACP reductase, where ACP stands for acyl carrier protein), which catalyses the last step in a sequence of four reactions that is repeated many times with each elongation step in the type II fatty acid biosynthesis pathway. The malarial parasite Plasmodi...

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Bibliografski detalji
Glavni autori: Kapoor, Mili, Reddy, C. Chandramouli, Krishnasastry, M. V., Surolia, Namita, Surolia, Avadhesha
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133881/
https://ncbi.nlm.nih.gov/pubmed/15086316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031821
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