Enzyme Mechanism and Slow-Onset Inhibition of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase by an Inorganic Complex

Malaria continues to be a major cause of children's morbidity and mortality worldwide, causing nearly one million deaths annually. The human malaria parasite, Plasmodium falciparum, synthesizes fatty acids employing the Type II fatty acid biosynthesis system (FAS II), unlike humans that rely on...

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Detalhes bibliográficos
Main Authors: de Medeiros, Patrícia Soares de Maria, Ducati, Rodrigo Gay, Basso, Luiz Augusto, Santos, Diógenes Santiago, da Silva, Luiz Hildebrando Pereira
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092583/
https://ncbi.nlm.nih.gov/pubmed/21603269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/642758
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