Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents

Recent studies have demonstrated that submicromolar concentrations of the biocide triclosan arrest the growth of the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii and inhibit the activity of the apicomplexan enoyl acyl carrier protein reductase (ENR). The crystal structures of T...

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Detalhes bibliográficos
Main Authors: Muench, Stephen P., Prigge, Sean T., McLeod, Rima, Rafferty, John B., Kirisits, Michael J., Roberts, Craig W., Mui, Ernest J., Rice, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483495/
https://ncbi.nlm.nih.gov/pubmed/17327670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444906053625
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