Identification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl Reductase

Toxoplasmosis causes significant morbidity and mortality and yet available medicines are limited by toxicities and hypersensitivity. Since improved medicines are needed urgently, rational approaches were used to identify novel lead compounds effective against Toxoplasma gondii enoyl reductase (TgENR...

Full description

Saved in:
Bibliographic Details
Main Authors: Tipparaju, Suresh K., Muench, Stephen P., Mui, Ernest J., Ruzheinikov, Sergey N., Lu, Jeffrey Z., Hutson, Samuel L., Kirisits, Michael J., Prigge, Sean T., Roberts, Craig W., Henriquez, Fiona L., Kozikowski, Alan P., Rice, David W., McLeod, Rima L.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932859/
https://ncbi.nlm.nih.gov/pubmed/20698542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9017724
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items