Identification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl Reductase

Toxoplasmosis causes significant morbidity and mortality and yet available medicines are limited by toxicities and hypersensitivity. Since improved medicines are needed urgently, rational approaches were used to identify novel lead compounds effective against Toxoplasma gondii enoyl reductase (TgENR...

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Bibliografiska uppgifter
Huvudupphovsmän: Tipparaju, Suresh K., Muench, Stephen P., Mui, Ernest J., Ruzheinikov, Sergey N., Lu, Jeffrey Z., Hutson, Samuel L., Kirisits, Michael J., Prigge, Sean T., Roberts, Craig W., Henriquez, Fiona L., Kozikowski, Alan P., Rice, David W., McLeod, Rima L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932859/
https://ncbi.nlm.nih.gov/pubmed/20698542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9017724
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