Relationship between Ceftolozane-Tazobactam Exposure and Drug Resistance Amplification in a Hollow-Fiber Infection Model

In an era of rapidly emerging antimicrobial-resistant bacteria, it is critical to understand the importance of the relationships among drug exposure, duration of therapy, and selection of drug resistance. Herein we describe the results of studies designed to determine the ceftolozane-tazobactam expo...

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Détails bibliographiques
Auteurs principaux: VanScoy, Brian, Mendes, Rodrigo E., Castanheira, Mariana, McCauley, Jennifer, Bhavnani, Sujata M., Forrest, Alan, Jones, Ronald N., Okusanya, Olanrewaju O., Friedrich, Lawrence V., Steenbergen, Judith, Ambrose, Paul G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754319/
https://ncbi.nlm.nih.gov/pubmed/23774429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00461-13
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