Relationship between Ceftolozane-Tazobactam Exposure and Drug Resistance Amplification in a Hollow-Fiber Infection Model

In an era of rapidly emerging antimicrobial-resistant bacteria, it is critical to understand the importance of the relationships among drug exposure, duration of therapy, and selection of drug resistance. Herein we describe the results of studies designed to determine the ceftolozane-tazobactam expo...

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Autori principali: VanScoy, Brian, Mendes, Rodrigo E., Castanheira, Mariana, McCauley, Jennifer, Bhavnani, Sujata M., Forrest, Alan, Jones, Ronald N., Okusanya, Olanrewaju O., Friedrich, Lawrence V., Steenbergen, Judith, Ambrose, Paul G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754319/
https://ncbi.nlm.nih.gov/pubmed/23774429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00461-13
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