Myxomavirus-Derived Serpin Prolongs Survival and Reduces Inflammation and Hemorrhage in an Unrelated Lethal Mouse Viral Infection

Lethal viral infections produce widespread inflammation with vascular leak, clotting, and bleeding (disseminated intravascular coagulation [DIC]), organ failure, and high mortality. Serine proteases in clot-forming (thrombotic) and clot-dissolving (thrombolytic) cascades are activated by an inflamma...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Hao, Zheng, Donghang, Abbott, Jeff, Liu, Liying, Bartee, Mee Y., Long, Maureen, Davids, Jennifer, Williams, Jennifer, Feldmann, Heinz, Strong, James, Grau, Katrina R., Tibbetts, Scott, Macaulay, Colin, McFadden, Grant, Thoburn, Robert, Lomas, David A., Spinale, Francis G., Virgin, Herbert W., Lucas, Alexandra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2013
Gaiak:
Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754305/
https://ncbi.nlm.nih.gov/pubmed/23774438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02594-12
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