The PHD/LAP-Domain Protein M153R of Myxomavirus Is a Ubiquitin Ligase That Induces the Rapid Internalization and Lysosomal Destruction of CD4

The genomes of several poxviruses contain open reading frames with homology to the K3 and K5 genes of Kaposi's sarcoma-associated herpesvirus (KSHV) and the K3 gene of murine gammaherpesvirus 68, which target major histocompatibility complex class I (MHC-I) as well as costimulatory molecules fo...

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Detalhes bibliográficos
Main Authors: Mansouri, Mandana, Bartee, Eric, Gouveia, Kristine, Hovey Nerenberg, Bianca T., Barrett, John, Thomas, Laurel, Thomas, Gary, McFadden, Grant, Früh, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140772/
https://ncbi.nlm.nih.gov/pubmed/12502858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1427-1440.2003
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