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The PHD/LAP-Domain Protein M153R of Myxomavirus Is a Ubiquitin Ligase That Induces the Rapid Internalization and Lysosomal Destruction of CD4

The genomes of several poxviruses contain open reading frames with homology to the K3 and K5 genes of Kaposi's sarcoma-associated herpesvirus (KSHV) and the K3 gene of murine gammaherpesvirus 68, which target major histocompatibility complex class I (MHC-I) as well as costimulatory molecules fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mansouri, Mandana, Bartee, Eric, Gouveia, Kristine, Hovey Nerenberg, Bianca T., Barrett, John, Thomas, Laurel, Thomas, Gary, McFadden, Grant, Früh, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140772/
https://ncbi.nlm.nih.gov/pubmed/12502858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1427-1440.2003
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