Serpin Treatment Suppresses Inflammatory Vascular Lesions in Temporal Artery Implants (TAI) from Patients with Giant Cell Arteritis

Giant cell arteritis (GCA) and Takayasu’s disease are inflammatory vasculitic syndromes (IVS) causing sudden blindness and widespread arterial obstruction and aneurysm formation. Glucocorticoids and aspirin are mainstays of treatment, predominantly targeting T cells. Serp-1, a Myxomavirus-derived se...

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發表在:PLoS One
Main Authors: Chen, Hao, Zheng, Donghang, Ambadapadi, Sriram, Davids, Jennifer, Ryden, Sally, Samy, Hazem, Bartee, Mee, Sobel, Eric, Dai, Erbin, Liu, Liying, Macaulay, Colin, Yachnis, Anthony, Weyand, Cornelia, Thoburn, Robert, Lucas, Alexandra
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319900/
https://ncbi.nlm.nih.gov/pubmed/25658487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115482
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