Serpin Treatment Suppresses Inflammatory Vascular Lesions in Temporal Artery Implants (TAI) from Patients with Giant Cell Arteritis

Giant cell arteritis (GCA) and Takayasu’s disease are inflammatory vasculitic syndromes (IVS) causing sudden blindness and widespread arterial obstruction and aneurysm formation. Glucocorticoids and aspirin are mainstays of treatment, predominantly targeting T cells. Serp-1, a Myxomavirus-derived se...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Hao, Zheng, Donghang, Ambadapadi, Sriram, Davids, Jennifer, Ryden, Sally, Samy, Hazem, Bartee, Mee, Sobel, Eric, Dai, Erbin, Liu, Liying, Macaulay, Colin, Yachnis, Anthony, Weyand, Cornelia, Thoburn, Robert, Lucas, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319900/
https://ncbi.nlm.nih.gov/pubmed/25658487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115482
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