Serpin Treatment Suppresses Inflammatory Vascular Lesions in Temporal Artery Implants (TAI) from Patients with Giant Cell Arteritis

Giant cell arteritis (GCA) and Takayasu’s disease are inflammatory vasculitic syndromes (IVS) causing sudden blindness and widespread arterial obstruction and aneurysm formation. Glucocorticoids and aspirin are mainstays of treatment, predominantly targeting T cells. Serp-1, a Myxomavirus-derived se...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Chen, Hao, Zheng, Donghang, Ambadapadi, Sriram, Davids, Jennifer, Ryden, Sally, Samy, Hazem, Bartee, Mee, Sobel, Eric, Dai, Erbin, Liu, Liying, Macaulay, Colin, Yachnis, Anthony, Weyand, Cornelia, Thoburn, Robert, Lucas, Alexandra
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319900/
https://ncbi.nlm.nih.gov/pubmed/25658487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115482
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