Capsid Antibodies to Different Adeno-Associated Virus Serotypes Bind Common Regions

Interactions between viruses and the host antibody immune response are critical in the development and control of disease, and antibodies are also known to interfere with the efficacy of viral vector-based gene delivery. The adeno-associated viruses (AAVs) being developed as vectors for corrective h...

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Bibliographische Detailangaben
Hauptverfasser: Gurda, Brittney L., DiMattia, Michael A., Miller, Edward B., Bennett, Antonette, McKenna, Robert, Weichert, Wendy S., Nelson, Christian D., Chen, Wei-jun, Muzyczka, Nicholas, Olson, Norman H., Sinkovits, Robert S., Chiorini, John A., Zolotutkhin, Sergei, Kozyreva, Olga G., Samulski, R. Jude, Baker, Timothy S., Parrish, Colin R., Agbandje-McKenna, Mavis
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754064/
https://ncbi.nlm.nih.gov/pubmed/23760240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00622-13
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