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Capsid Antibodies to Different Adeno-Associated Virus Serotypes Bind Common Regions

Interactions between viruses and the host antibody immune response are critical in the development and control of disease, and antibodies are also known to interfere with the efficacy of viral vector-based gene delivery. The adeno-associated viruses (AAVs) being developed as vectors for corrective h...

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Autors principals: Gurda, Brittney L., DiMattia, Michael A., Miller, Edward B., Bennett, Antonette, McKenna, Robert, Weichert, Wendy S., Nelson, Christian D., Chen, Wei-jun, Muzyczka, Nicholas, Olson, Norman H., Sinkovits, Robert S., Chiorini, John A., Zolotutkhin, Sergei, Kozyreva, Olga G., Samulski, R. Jude, Baker, Timothy S., Parrish, Colin R., Agbandje-McKenna, Mavis
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754064/
https://ncbi.nlm.nih.gov/pubmed/23760240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00622-13
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