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Capsid Antibodies to Different Adeno-Associated Virus Serotypes Bind Common Regions

Interactions between viruses and the host antibody immune response are critical in the development and control of disease, and antibodies are also known to interfere with the efficacy of viral vector-based gene delivery. The adeno-associated viruses (AAVs) being developed as vectors for corrective h...

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Main Authors: Gurda, Brittney L., DiMattia, Michael A., Miller, Edward B., Bennett, Antonette, McKenna, Robert, Weichert, Wendy S., Nelson, Christian D., Chen, Wei-jun, Muzyczka, Nicholas, Olson, Norman H., Sinkovits, Robert S., Chiorini, John A., Zolotutkhin, Sergei, Kozyreva, Olga G., Samulski, R. Jude, Baker, Timothy S., Parrish, Colin R., Agbandje-McKenna, Mavis
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754064/
https://ncbi.nlm.nih.gov/pubmed/23760240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00622-13
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