Structure and Dynamics of Adeno-Associated Virus Serotype 1 VP1-Unique N-Terminal Domain and Its Role in Capsid Trafficking

The importance of the phospholipase A(2) domain located within the unique N terminus of the capsid viral protein VP1 (VP1u) in parvovirus infection has been reported. This study used computational methods to characterize the VP1 sequence for adeno-associated virus (AAV) serotypes 1 to 12 and circula...

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Autori principali: Venkatakrishnan, Balasubramanian, Yarbrough, Joseph, Domsic, John, Bennett, Antonette, Bothner, Brian, Kozyreva, Olga G., Samulski, R. Jude, Muzyczka, Nicholas, McKenna, Robert, Agbandje-McKenna, Mavis
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Structure and Assembly
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624325/
https://ncbi.nlm.nih.gov/pubmed/23427155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02524-12
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