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Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking

The single-stranded DNA (ssDNA) parvoviruses enter host cells through receptor-mediated endocytosis, and infection depends on processing in the early to late endosome as well as in the lysosome prior to nuclear entry for replication. However, the mechanisms of capsid endosomal processing, including...

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Detalhes bibliográficos
Main Authors: Nam, Hyun-Joo, Gurda, Brittney L., McKenna, Robert, Potter, Mark, Byrne, Barry, Salganik, Maxim, Muzyczka, Nicholas, Agbandje-McKenna, Mavis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209291/
https://ncbi.nlm.nih.gov/pubmed/21900159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05305-11
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