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Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking

The single-stranded DNA (ssDNA) parvoviruses enter host cells through receptor-mediated endocytosis, and infection depends on processing in the early to late endosome as well as in the lysosome prior to nuclear entry for replication. However, the mechanisms of capsid endosomal processing, including...

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Autores principales: Nam, Hyun-Joo, Gurda, Brittney L., McKenna, Robert, Potter, Mark, Byrne, Barry, Salganik, Maxim, Muzyczka, Nicholas, Agbandje-McKenna, Mavis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209291/
https://ncbi.nlm.nih.gov/pubmed/21900159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05305-11
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