Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking

The single-stranded DNA (ssDNA) parvoviruses enter host cells through receptor-mediated endocytosis, and infection depends on processing in the early to late endosome as well as in the lysosome prior to nuclear entry for replication. However, the mechanisms of capsid endosomal processing, including...

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Bibliographische Detailangaben
Hauptverfasser: Nam, Hyun-Joo, Gurda, Brittney L., McKenna, Robert, Potter, Mark, Byrne, Barry, Salganik, Maxim, Muzyczka, Nicholas, Agbandje-McKenna, Mavis
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209291/
https://ncbi.nlm.nih.gov/pubmed/21900159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05305-11
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