Capsid Antibodies to Different Adeno-Associated Virus Serotypes Bind Common Regions

Interactions between viruses and the host antibody immune response are critical in the development and control of disease, and antibodies are also known to interfere with the efficacy of viral vector-based gene delivery. The adeno-associated viruses (AAVs) being developed as vectors for corrective h...

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Main Authors: Gurda, Brittney L., DiMattia, Michael A., Miller, Edward B., Bennett, Antonette, McKenna, Robert, Weichert, Wendy S., Nelson, Christian D., Chen, Wei-jun, Muzyczka, Nicholas, Olson, Norman H., Sinkovits, Robert S., Chiorini, John A., Zolotutkhin, Sergei, Kozyreva, Olga G., Samulski, R. Jude, Baker, Timothy S., Parrish, Colin R., Agbandje-McKenna, Mavis
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
主題:
Structure and Assembly
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754064/
https://ncbi.nlm.nih.gov/pubmed/23760240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00622-13
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