載入...

Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

The conserved HIV-1 site of coreceptor binding is protected from antibody-directed neutralization by conformational and steric restrictions. While inaccessible to most human antibodies, the coreceptor site has been shown to be accessed by antibody fragments. In this study, we used X-ray crystallogra...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Acharya, Priyamvada, Luongo, Timothy S., Georgiev, Ivelin S., Matz, Julie, Schmidt, Stephen D., Louder, Mark K., Kessler, Pascal, Yang, Yongping, McKee, Krisha, O'Dell, Sijy, Chen, Lei, Baty, Daniel, Chames, Patrick, Martin, Loïc, Mascola, John R., Kwong, Peter D.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753989/
https://ncbi.nlm.nih.gov/pubmed/23843638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01332-13
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!