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Straightforward Selection of Broadly Neutralizing Single-Domain Antibodies Targeting the Conserved CD4 and Coreceptor Binding Sites of HIV-1 gp120
Few broadly neutralizing antibodies targeting determinants of the HIV-1 surface envelope glycoprotein (gp120) involved in sequential binding to host CD4 and chemokine receptors have been characterized. While these epitopes show low diversity among various isolates, HIV-1 employs many strategies to e...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
American Society for Microbiology
2013
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3554102/ https://ncbi.nlm.nih.gov/pubmed/23152508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00461-12 |
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