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Expression and processing of fluorescent fusion proteins of amyloid precursor protein (APP)()
Processing of β-amyloid precursor protein (APP) by β- and γ-secretases in neurons produces amyloid-β (Aβ), whose excess accumulation leads to Alzheimer’s disease (AD). Knowledge on subcellular trafficking pathways of APP and its fragments is important for the understanding of AD pathogenesis. We des...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753662/ https://ncbi.nlm.nih.gov/pubmed/23517619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.03.003 |
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