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The role of aromatic interactions in amyloid formation by islet amyloid polypeptide

Aromatic-aromatic and aromatic-hydrophobic interactions have been proposed to play a role in amyloid formation by a range of polypeptides including islet amyloid polypeptide (IAPP, Amylin). IAPP is responsible for amyloid formation during type-2 diabetes. The polypeptide is 37 residues in length and...

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Bibliographic Details
Main Authors: Tu, Ling-Hsien, Raleigh, Daniel P.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753198/
https://ncbi.nlm.nih.gov/pubmed/23256729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3014278
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