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Immediate and Delayed Consequences of Xanomeline Wash-Resistant Binding at the M3 Muscarinic Receptor

Xanomeline is thought to be a M1/M4 functionally selective agonist at muscarinic receptors. We have previously demonstrated that it binds in a unique manner at the M1 receptor. In the current study, we examined the ability of xanomeline to bind to the M3 receptor and determined the long-term consequ...

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Hlavní autoři: Noetzel, Meredith J., Grant, Marianne K. O., El-Fakahany, Esam E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752336/
https://ncbi.nlm.nih.gov/pubmed/19082883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-008-9886-3
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