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Mechanisms of M3 Muscarinic Receptor Regulation by Wash-Resistant Xanomeline Binding
BACKGROUND/AIMS: Xanomeline has been shown to bind in a unique manner at M1 and M3 muscarinic receptors, with interactions at both the orthosteric site and an allosteric site. We have previously shown that brief exposure of Chinese hamster ovary cells that express the M3 receptor to xanomeline follo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
S. Karger AG
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835379/ https://ncbi.nlm.nih.gov/pubmed/19401618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000214843 |
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