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Mechanisms of M3 Muscarinic Receptor Regulation by Wash-Resistant Xanomeline Binding

BACKGROUND/AIMS: Xanomeline has been shown to bind in a unique manner at M1 and M3 muscarinic receptors, with interactions at both the orthosteric site and an allosteric site. We have previously shown that brief exposure of Chinese hamster ovary cells that express the M3 receptor to xanomeline follo...

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Bibliografiske detaljer
Main Authors: Noetzel, Meredith J., Grant, Marianne K.O., El-Fakahany, Esam E.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835379/
https://ncbi.nlm.nih.gov/pubmed/19401618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000214843
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