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Pharmacological Evaluation of the Long-Term Effects of Xanomeline on the M(1) Muscarinic Acetylcholine Receptor
Xanomeline is a unique agonist of muscarinic receptors that possesses functional selectivity at the M(1) and M(4) receptor subtypes. It also exhibits wash-resistant binding to and activation of the receptor. In the present work we investigated the consequences of this type of binding of xanomeline o...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009740/ https://ncbi.nlm.nih.gov/pubmed/21203415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015722 |
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