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Human RNase H1 Is Associated with Protein P32 and Is Involved in Mitochondrial Pre-rRNA Processing

Mammalian RNase H1 has been implicated in mitochondrial DNA replication and RNA processing and is required for embryonic development. We identified the mitochondrial protein P32 that binds specifically to human RNase H1, but not human RNase H2. P32 binds human RNase H1 via the hybrid-binding domain...

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Detalhes bibliográficos
Main Authors: Wu, Hongjiang, Sun, Hong, Liang, Xuehai, Lima, Walt F., Crooke, Stanley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750045/
https://ncbi.nlm.nih.gov/pubmed/23990920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071006
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