Accurate processing of human pre-rRNA in vitro.

We report here that the mature 5' terminus of human 18S rRNA is generated in vitro by a two-step processing reaction. In the first step, SP6 transcripts were specifically cleaved in HeLa cell nucleolar extract at three positions near the external transcribed spacer (ETS)-18S boundary. Of these...

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Detalhes bibliográficos
Main Authors: Hannon, G J, Maroney, P A, Branch, A, Benenfield, B J, Robertson, H D, Nilsen, T W
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC362525/
https://ncbi.nlm.nih.gov/pubmed/2586517
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