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mTOR signaling regulates the processing of pre-rRNA in human cells

Signaling through the mammalian target of rapamycin, complex 1 (mTORC1), positively regulates the transcription of ribosomal RNA (rRNA) and the synthesis of ribosomal proteins, thereby promoting the complex process of ribosome biogenesis. The major rRNAs are transcribed as a single precursor, which...

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Bibliografske podrobnosti
Main Authors: Iadevaia, Valentina, Zhang, Ze, Jan, Eric, Proud, Christopher G.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315323/
https://ncbi.nlm.nih.gov/pubmed/22121221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1040
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