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Force and kinetic barriers to unzipping of the DNA double helix
A theory of the unzipping of double-stranded DNA is presented and is compared to recent micromanipulation experiments. It is shown that the interactions that stabilize the double helix and the elastic rigidity of single strands simply determine the sequence-dependent ≈12-pN force threshold for DNA s...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC37483/ https://ncbi.nlm.nih.gov/pubmed/11447279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151257598 |
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