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Reconstruction and Identification of DNA Sequence Landscapes from Unzipping Experiments at Equilibrium
Two methods for reconstructing the free-energy landscape of a DNA molecule from the knowledge of the equilibrium unzipping force versus extension signal are introduced: a simple and fast procedure, based on a parametric representation of the experimental force signal, and a maximum-likelihood infere...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907261/ https://ncbi.nlm.nih.gov/pubmed/24461018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.4496 |
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