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Global force-torque phase diagram for the DNA double helix: structural transitions, triple points and collapsed plectonemes

We present a free energy model for structural transitions of the DNA double helix driven by tensile and torsional stress. Our model is coarse grained, and is based on semiflexible polymer descriptions of B-DNA, underwound L-DNA, and highly overwound P-DNA. The statistical-mechanical model of plecton...

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Autors principals: Marko, John F., Neukirch, Sébastien
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936674/
https://ncbi.nlm.nih.gov/pubmed/24483501
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