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Force and kinetic barriers to unzipping of the DNA double helix

A theory of the unzipping of double-stranded DNA is presented and is compared to recent micromanipulation experiments. It is shown that the interactions that stabilize the double helix and the elastic rigidity of single strands simply determine the sequence-dependent ≈12-pN force threshold for DNA s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cocco, Simona, Monasson, Rémi, Marko, John F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC37483/
https://ncbi.nlm.nih.gov/pubmed/11447279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151257598
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