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Characterization of FKGK18 as Inhibitor of Group VIA Ca(2+)-Independent Phospholipase A(2) (iPLA(2)β): Candidate Drug for Preventing Beta-Cell Apoptosis and Diabetes
Ongoing studies suggest an important role for iPLA(2)β in a multitude of biological processes and it has been implicated in neurodegenerative, skeletal and vascular smooth muscle disorders, bone formation, and cardiac arrhythmias. Thus, identifying an iPLA(2)βinhibitor that can be reliably and safel...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748103/ https://ncbi.nlm.nih.gov/pubmed/23977134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071748 |
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