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Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II
Promoter-proximal pausing by RNA polymerase II (Pol II) ensures both gene-specific regulation and RNA quality control. Structural considerations suggested initiation factor eviction would be required for elongation factor engagement and pausing of transcription complexes. Here we show that selective...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746743/ https://ncbi.nlm.nih.gov/pubmed/23064645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2399 |
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