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A Cdk9-PP1 switch regulates the elongation-termination transition of RNA polymerase II

The end of the RNA polymerase II (Pol II) transcription cycle is strictly regulated to prevent interference between neighbouring genes and safeguard transcriptome integrity(1). Pol II accumulation downstream of the cleavage and polyadenylation signal (CPS) can facilitate recruitment of factors invol...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Parua, Pabitra K., Booth, Gregory T., Sansó, Miriam, Benjamin, Bradley, Tanny, Jason C., Lis, John T., Fisher, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021199/
https://ncbi.nlm.nih.gov/pubmed/29899453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0214-z
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