A carregar...

Distinct Cdk9-phosphatase switches act at the beginning and end of elongation by RNA polymerase II

Reversible phosphorylation of Pol II and accessory factors helps order the transcription cycle. Here, we define two kinase-phosphatase switches that operate at different points in human transcription. Cdk9/cyclin T1 (P-TEFb) catalyzes inhibitory phosphorylation of PP1 and PP4 complexes that localize...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Parua, Pabitra K., Kalan, Sampada, Benjamin, Bradley, Sansó, Miriam, Fisher, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455706/
https://ncbi.nlm.nih.gov/pubmed/32859893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18173-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!