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RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes

We investigated co-transcriptional recruitment of pre-mRNA processing factors to human genes. Capping factors associate with paused RNA pol II at the 5′ ends of quiescent genes. They also track throughout actively transcribed genes, and accumulate with paused polymerase in the 3′ flanking region. 3′...

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Autori principali: Glover-Cutter, Kira, Kim, Soojin, Espinosa, Joaquin, Bentley, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836588/
https://ncbi.nlm.nih.gov/pubmed/18157150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1352
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