Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency

Cellular stress or injury can result in mitochondrial dysfunction, which has been linked to many chronic neurological disorders including amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). Stressed and dysfunctional mitochondria exhibit an increase in large conductance mitochondrial m...

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Bibliografski detalji
Glavni autori: Alavian, Kambiz N., Dworetzky, Steven I., Bonanni, Laura, Zhang, Ping, Sacchetti, Silvio, Mariggio, Maria A., Onofrj, Marco, Thomas, Astrid, Li, Hongmei, Mangold, Jamie E., Signore, Armando P., DeMarco, Ulrike, Demady, Damon R., Nabili, Panah, Lazrove, Emma, Smith, Peter J.S., Gribkoff, Valentin K., Jonas, Elizabeth A.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746080/
https://ncbi.nlm.nih.gov/pubmed/22364637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.01.046
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