The Need for New Approaches in CNS Drug Discovery: Why Drugs Have Failed, and What Can Be Done to Improve Outcomes

Por Gribkoff, Valentin K., Kaczmarek, Leonard K.
Publicado no Neuropharmacology (2016)

KNS‐760704 [(6R)‐4,5,6,7‐tetrahydro‐N6‐propyl‐2, 6‐benzothiazole‐diamine dihydrochloride monohydrate] for the Treatment of Amyotrophic Lateral Sclerosis

Por Gribkoff, Valentin K., Bozik, Michael E.
Publicado no CNS Neurosci Ther (2008)

Long-Lasting Functional Disabilities in Middle-Aged Rats with Small Cerebral Infarcts

Por Lindner, Mark D., Gribkoff, Valentin K., Donlan, Nicole A., Jones, Theresa A.
Publicado no J Neurosci (2003)

Phase Shifting of Circadian Rhythms and Depression of Neuronal Activity in the Rat Suprachiasmatic Nucleus by Neuropeptide Y: Mediation by Different Receptor Subtypes

Por Gribkoff, Valentin K., Pieschl, Rick L., Wisialowski, Todd A., van den Pol, Anthony N., Yocca, Frank D.
Publicado no J Neurosci (1998)

Targeted Disruption of the Mouse Mel(1b) Melatonin Receptor

Por Jin, Xiaowei, von Gall, Charlotte, Pieschl, Rick L., Gribkoff, Valentin K., Stehle, Jorg H., Reppert, Steven M., Weaver, David R.
Publicado em 2003

Phenotypic Alteration of a Human BK (hSlo) Channel byhSloβ Subunit Coexpression: Changes in Blocker Sensitivity, Activation/Relaxation and Inactivation Kinetics, and Protein Kinase...

Por Dworetzky, Steven I., Boissard, Christopher G., Lum-Ragan, Janet T., McKay, M. Craig, Post-Munson, Debra J., Trojnacki, Joanne T., Chang, Chia-Ping, Gribkoff, Valentin K.
Publicado no J Neurosci (1996)

The Mitochondrial Complex V–Associated Large-Conductance Inner Membrane Current Is Regulated by Cyclosporine and Dexpramipexole

Por Alavian, Kambiz N., Dworetzky, Steven I., Bonanni, Laura, Zhang, Ping, Sacchetti, Silvio, Li, Hongmei, Signore, Armando P., Smith, Peter J. S., Gribkoff, Valentin K., Jonas, Elizabeth A.
Publicado no Mol Pharmacol (2015)

Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency

Por Alavian, Kambiz N., Dworetzky, Steven I., Bonanni, Laura, Zhang, Ping, Sacchetti, Silvio, Mariggio, Maria A., Onofrj, Marco, Thomas, Astrid, Li, Hongmei, Mangold, Jamie E., Signore, Armando P., DeMarco, Ulrike, Demady, Damon R., Nabili, Panah, Lazrove, Emma, Smith, Peter J.S., Gribkoff, Valentin K., Jonas, Elizabeth A.
Publicado em 2012

ATP synthase c-subunit leak causes aberrant cellular metabolism in Fragile X syndrome

Por Licznerski, Pawel, Park, Han-A, Rolyan, Harshvardhan, Chen, Rongmin, Mnatsakanyan, Nelli, Miranda, Paige, Graham, Morven, Wu, Jing, Cruz-Reyes, Nicole, Mehta, Nikita, Sohail, Sana, Salcedo, Jorge, Song, Erin, Effman, Charles, Effman, Samuel, Brandao, Lucas, Xu, Gulan N., Braker, Amber, Gribkoff, Valentin K., Levy, Richard J., Jonas, Elizabeth A.
Publicado no Cell (2020)