Targeted Disruption of the Mouse Mel(1b) Melatonin Receptor

Two high-affinity, G protein-coupled melatonin receptor subtypes have been identified in mammals. Targeted disruption of the Mel(1a) melatonin receptor prevents some, but not all, responses to the hormone, suggesting functional redundancy among receptor subtypes (Liu et al., Neuron 19:91-102, 1997)....

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Bibliographic Details
Main Authors: Jin, Xiaowei, von Gall, Charlotte, Pieschl, Rick L., Gribkoff, Valentin K., Stehle, Jorg H., Reppert, Steven M., Weaver, David R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC140714/
https://ncbi.nlm.nih.gov/pubmed/12529409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.3.1054-1060.2003
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