Targeted Disruption of the Mouse Mel(1b) Melatonin Receptor

Two high-affinity, G protein-coupled melatonin receptor subtypes have been identified in mammals. Targeted disruption of the Mel(1a) melatonin receptor prevents some, but not all, responses to the hormone, suggesting functional redundancy among receptor subtypes (Liu et al., Neuron 19:91-102, 1997)....

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Main Authors: Jin, Xiaowei, von Gall, Charlotte, Pieschl, Rick L., Gribkoff, Valentin K., Stehle, Jorg H., Reppert, Steven M., Weaver, David R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC140714/
https://ncbi.nlm.nih.gov/pubmed/12529409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.3.1054-1060.2003
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