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An uncoupling channel within the c-subunit ring of the F(1)F(O) ATP synthase is the mitochondrial permeability transition pore
Mitochondria maintain tight regulation of inner mitochondrial membrane (IMM) permeability to sustain ATP production. Stressful events cause cellular calcium (Ca(2+)) dysregulation followed by rapid loss of IMM potential known as permeability transition (PT), which produces osmotic shifts, metabolic...
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मुख्य लेखकों: | , , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
National Academy of Sciences
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4115574/ https://ncbi.nlm.nih.gov/pubmed/24979777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401591111 |
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