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Dexpramipexole improves bioenergetics and outcome in experimental stroke
BACKGROUND AND PURPOSE: Dexpramipexole, a drug recently tested in patients with amyotrophic lateral sclerosis (ALS,) is able to bind F1Fo ATP synthase and increase mitochondrial ATP production. Here, we have investigated its effects on experimental ischaemic brain injury. EXPERIMENTAL APPROACH: The...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758384/ https://ncbi.nlm.nih.gov/pubmed/28320070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13790 |
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