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Neuroprotection induced by dexpramipexole delays disease progression in a mouse model of progressive multiple sclerosis

BACKGROUND AND PURPOSE: Drugs able to counteract progressive multiple sclerosis (MS) represent a largely unmet therapeutic need. Even though the pathogenesis of disease evolution is still obscure, accumulating evidence indicates that mitochondrial dysfunction plays a causative role in neurodegenerat...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Buonvicino, Daniela, Ranieri, Giuseppe, Pratesi, Sara, Gerace, Elisabetta, Muzzi, Mirko, Guasti, Daniele, Tofani, Lorenzo, Chiarugi, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312322/
https://ncbi.nlm.nih.gov/pubmed/32199028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15058
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