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RNA interference-based therapeutics for human immunodeficiency virus HIV-1 treatment: synthetic siRNA or vector-based shRNA?

IMPORTANCE OF THE FIELD: Despite the extraordinary clinical benefits of HAART, the prospect of life-long antiretroviral regimen poses significant practical problems, which has spurred an interest in developing new drugs and strategies to treat HIV infection and to eliminate persistent viral reservoi...

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Detalles Bibliográficos
Main Authors: Subramanya, Sandesh, Kim, Sang-Soo, Manjunath, N, Shankar, Premlata
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745298/
https://ncbi.nlm.nih.gov/pubmed/20088715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712590903448158
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