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A Comparison of Target Gene Silencing using Synthetically Modified siRNA and shRNA That Express Recombinant Lentiviral Vectors

RNA-interference is an effective natural mechanism of post-transcriptional modulation of gene expression. RNA-interference mechanism exist as in high eukaryotes both animals and plants as well in lower eukaryotes and viruses. RNA-interference is now used as a powerful tool in study of functional gen...

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Detalhes bibliográficos
Main Authors: Spirin, P.V., Baskaran, D., Rubtsov, P.M., Zenkova, M.A., Vlassov, V.V., Chernolovskaya, E.L., Prassolov, V.S.
Formato: Artigo
Idioma:Inglês
Publicado em: A.I. Gordeyev 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347522/
https://ncbi.nlm.nih.gov/pubmed/22649608
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