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Silencing of Cav1.2 gene in neonatal cardiomyocytes by lentiviral delivered shRNA
Cav1.2 (α(1C)) and Cav1.3 (α(1D)) L-type Ca channels are co-expressed in the heart. To date, there are no pharmacological or biophysical tools to separate α(1D) from α(1C) Ca currents (I(Ca-L)) in cardiomyocytes. Here, we established a physiological model to study α(1D) I(Ca-L) in native myocytes us...
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Gepubliceerd in: | Biochem Biophys Res Commun |
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Hoofdauteurs: | , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4334931/ https://ncbi.nlm.nih.gov/pubmed/19422800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.04.150 |
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