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Targeted Delivery of siRNA to Macrophages for Anti-inflammatory Treatment
Inflammation mediated by tumor necrosis factor-α (TNF-α) and the associated neuronal apoptosis characterizes a number of neurologic disorders. Macrophages and microglial cells are believed to be the major source of TNF-α in the central nervous system (CNS). Here, we show that suppression of TNF-α by...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890121/ https://ncbi.nlm.nih.gov/pubmed/20216529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.27 |
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