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A Single siRNA Suppresses Fatal Encephalitis Induced by Two Different Flaviviruses

BACKGROUND: Japanese encephalitis virus (JEV) and West Nile virus (WNV) are neurotropic flaviviruses that can cause acute encephalitis with a high fatality rate. Currently there is no effective treatment for these infections. METHODS AND FINDINGS: We tested RNA interference (RNAi)-based intervention...

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Autors principals: Kumar, Priti, Lee, Sang Kyung, Shankar, Premlata, Manjunath, N
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1361782/
https://ncbi.nlm.nih.gov/pubmed/16464133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030096
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