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Cell-Selective Biological Activity of Rhodium Metalloinsertors Correlates with Subcellular Localization
Deficiencies in the mismatch repair (MMR) pathway are associated with several types of cancers, as well as resistance to commonly used chemotherapeutics. Rhodium metalloinsertors have been found to bind DNA mismatches with high affinity and specificity in vitro, and also exhibit cell-selective cytot...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740518/ https://ncbi.nlm.nih.gov/pubmed/23137296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3090687 |
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