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Cell-Selective Biological Activity of Rhodium Metalloinsertors Correlates with Subcellular Localization

Deficiencies in the mismatch repair (MMR) pathway are associated with several types of cancers, as well as resistance to commonly used chemotherapeutics. Rhodium metalloinsertors have been found to bind DNA mismatches with high affinity and specificity in vitro, and also exhibit cell-selective cytot...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Komor, Alexis C., Schneider, Curtis J., Weidmann, Alyson G., Barton, Jacqueline K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740518/
https://ncbi.nlm.nih.gov/pubmed/23137296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3090687
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