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Cell-Selective Biological Activity of Rhodium Metalloinsertors Correlates with Subcellular Localization

Deficiencies in the mismatch repair (MMR) pathway are associated with several types of cancers, as well as resistance to commonly used chemotherapeutics. Rhodium metalloinsertors have been found to bind DNA mismatches with high affinity and specificity in vitro, and also exhibit cell-selective cytot...

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Detalhes bibliográficos
Main Authors: Komor, Alexis C., Schneider, Curtis J., Weidmann, Alyson G., Barton, Jacqueline K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740518/
https://ncbi.nlm.nih.gov/pubmed/23137296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3090687
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